PHYSICOCHEMICAL AND TOXICITY ANALYSES OF FIVE NATRON (KANWA) VARIETIES SAMPLED FROM KURMI MARKET KANO, NORTHERN NIGERIA

  • T. S. Imam Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.
  • A. Hassan Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.
  • A. Sani Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.
  • B. H. Diyauddeen Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

Abstract

Natron, locally called kanwa in Hausa language is one of the commonly used food condiments. The physicochemical properties and sub-acute toxicity effects of five varieties sampled from Kano, Kurmi market were investigated.pH, Electrical Conductivity (EC), Cadmium and Lead concentrations in natron and natron-fed
rat blood samples were determined following standard protocols. Sub acute toxicity of five natron samples were evaluated on 11 groups of Wistar albino rats (R.novergicus) of 3 replicates each which were challenged with natron at various concentrations with the exception of control group. Biochemical assays of serum for ALT (Alanine aminotransferase) and AST (Aspartate aminotransferase) enzymes were determined following standard protocols. Results for mean pH values obtained for all samples ranged from 8.10 (in ungurnu) to 9.66 (in jar kanwa), found to be within the WHO set limit of 6.85-9.20. Values for EC obtained ranged from 123.37?s/cm (in farar kanwa) to 274.05?s/cm (in ungurnu), also found to be within the WHO set limit of 300?s/cm. Mean values for Cd in natron ranged from 2.39mg/kg (in ungurnu) to 3.13mg/kg (in jar kanwa), exceeded the WHO set limit of 0.20mg/kg, Pb values obtained ranged from 11.12mg/kg (in farar kanwa) to 15.70mg/kg (in mangul) also exceeded the WHO set limit of 10.00mg/kg. Sub-acute toxicity test revealed no mortality after 14 days experimental period. ALT values obtained ranged from 36.7u/L to 48.08u/L, showing increase in their activity compared with control (36.13u/L). AST values ranged from 6.80 to 42.76 u/L exceeded the values of control (6.41u/L). Farar kanwa and manda were found to be less toxic. Findings of this research suggests that natron play significant role in hepatoxicity and nephrotoxicity

Author Biographies

T. S. Imam, Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

A. Hassan, Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

A. Sani, Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

B. H. Diyauddeen, Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

Department of Biological Sciences, Bayero University, Kano. P.M.B 3011. Kano, Nigeria.

How to Cite
IMAM, T. S. et al. PHYSICOCHEMICAL AND TOXICITY ANALYSES OF FIVE NATRON (KANWA) VARIETIES SAMPLED FROM KURMI MARKET KANO, NORTHERN NIGERIA. SAU Science-Tech Journal, [S.l.], v. 4, n. 1, p. 1- 13, mar. 2020. ISSN 2659-1529. Available at: <https://journals.sau.edu.ng/index.php/sjbas/article/view/117>. Date accessed: 02 june 2020.
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